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Psychedelics: how they act on the brain to relieve depression

By Clare Tweedy, Teaching Fellow in Neuroscience, University of Leeds

Up to 30% of people with depression don’t respond to treatment with antidepressants. This may be down to differences in biology between patients and the fact that it often takes a long time to respond to the drugs – with some people giving up after a while. So there is an urgent need to expand the repertoire of drugs available to people with depression.

In recent years, attention has turned to psychedelics such as psilocybin,…

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