The science of weight loss – and why your brain is wired to keep you fat

By Valdemar Brimnes Ingemann Johansen, PhD Fellow in the Faculty of Health and Medical Sciences, University of Copenhagen
Christoffer Clemmensen, Associate Professor and Group Leader, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen

For decades, we’ve been told that weight loss is a matter of willpower: eat less, move more. But modern science has proven this isn’t actually the case.

More on that in a moment. But first, let’s go back a few hundred thousand years to examine our early human ancestors. Because we can blame a lot of the difficulty we have with weight loss today on our predecessors of the past – maybe the ultimate case of blame the parents.

For our…

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