Pregnant women face tough choices about medication use due to lack of safety data − here’s why medical research cuts will make it worse

By Almut Winterstein, Distinguished Professor of Pharmaceutical Outcomes & Policy, University of Florida
Sonja Rasmussen, Professor of Genetic Medicine, Johns Hopkins University

A panel convened in July 2025 by the Food and Drug Administration sparked controversy by casting doubt about the safety of commonly used antidepressants during pregnancy. But it also raised the broader issue of how little is known about the safety of many medications used in pregnancy, considering the implications for both mother and child – and how understudied this topic is.

In the U.S., the average pregnant patient takes four prescription medications,…

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