Gwada-negative: the rarest blood group on Earth

By Martin L. Olsson, Medical Director of the Nordic Reference Laboratory for Blood Group Genomics, Region Skåne & Professor of Transfusion Medicine, Head of the Division, Lund University
Jill Storry, Adjunct Professor, Division of Transfusion Medicine, Lund University

In a routine blood test that turned extraordinary, French scientists have identified the world’s newest and rarest blood group. The sole known carrier is a woman from Guadeloupe whose blood is so unique that doctors couldn’t find a single compatible donor.

The discovery of the 48th recognised blood group, called “Gwada-negative”, began when the woman’s blood plasma reacted against every potential donor sample tested, including those from her own siblings. Consequently, it was impossible to find a suitable…

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