New insights from biology can help overcome siloed thinking in cancer clinical trials and treatment

By Gerald Denis, Professor of Medicine and Pharmacology, Boston University

Rarely does an oncologist closely question a breast cancer patient about their blood glucose, body weight, lipid profile, or medications for diabetes and cardiovascular disease. Instead, these issues are usually the concern of the patient’s primary care provider.

Medical experts have recognized that obesity, defined as a body mass index of 30 or greater, increases the risk of several cancers. They include cancers of the breast, esophagus, kidney, gallbladder,…

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