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Drug Combination Controls HIV in Mice by Targeting Hidden Virus

Antiretroviral therapies work well to keep HIV infection at bay. As soon as the drugs are discontinued, though, the AIDS virus comes roaring back in a matter of weeks. Now, researchers have developed a treatment that attacks hidden HIV so there is no rebound when antiviral drugs are stopped. Using mice that were genetically bred to become infected with the AIDS virus, researchers have managed to access and unmask latent reservoirs of HIV and destroy them. In more than half of the rodents,...

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